Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | TNKS | O95271 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106735 | 0.76 | KDM4E (0.43) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL11868950 | 0.75 | KDM4E (0.54) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL14501908 | 0.75 | MEN1 (0.60) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL8797747 | 0.75 | POLB (0.55) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL7623370 | 0.75 | CUL4A (0.67) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL7623510 | 0.75 | MAPT (0.65) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL11863327 | 0.75 | KDM4E (0.57) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL11870722 | 0.75 | KDM4E (0.64) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL11816931 | 0.74 | MAPT (0.59) | KMT2AMEN1KDM4EMAPTTNKS | |
| SCHEMBL4489136 | 0.72 | KMT2A (0.57) | KMT2AMEN1KDM4EMAPTTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258138-A | Method of foaming thermoplastic polymeric materials using tetrazole-containing heterocycles | THE DOW CHEMICAL COMPANY (US) | 1981-03-24 | — | — | US | claimed |
| US-3988455-A | Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | claimed |
| US-4258138-A | Method of foaming thermoplastic polymeric materials using tetrazole-containing heterocycles | THE DOW CHEMICAL COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-3988455-A | Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3988455-A | Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3988455-A | Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |