SCHEMBL11326348

SCHEMBL11326348

Nc1ccc(S(=O)(=O)c2ccccc2S(N)(=O)=O)cc1C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.48
CA12 O43570 3/20 0.47
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA4 P22748 3/20 0.47
CA6 P23280 3/20 0.47
CA5A P35218 3/20 0.47
CA7 P43166 3/20 0.47
CA9 Q16790 3/20 0.47
CA14 Q9ULX7 3/20 0.47
CA5B Q9Y2D0 3/20 0.47
FFAR1 O14842 3/20 0.44
CYP2C9 P11712 1/20 0.43
PTGES2 Q9H7Z7 2/20 0.42
HSD11B1 P28845 1/20 0.42
HTR6 P50406 1/20 0.40
KIF11 P52732 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11328019 0.88 CA2 (0.47) FFAR4CA12CA1CA2CA4
SCHEMBL11328006 0.83 FFAR4 (0.51) FFAR4CA12CA1CA2CA4
SCHEMBL2810971 0.82 FFAR4 (0.54) FFAR4CA12CA1CA2CA4
SCHEMBL11326167 0.81 FFAR4 (0.43) FFAR4CA12CA1CA2CA4
SCHEMBL11685070 0.81 CA12 (0.58) FFAR4CA12CA1CA2CA4
SCHEMBL11326170 0.80 FFAR4 (0.47) FFAR4CA12CA1CA2CA4
SCHEMBL11326171 0.80 FFAR4 (0.43) FFAR4CA12CA1CA2CA4
SCHEMBL11323129 0.79 FFAR4 (0.41) FFAR4CA12CA1CA2CA4
SCHEMBL11328014 0.79 FFAR4 (0.46) FFAR4CA12CA1CA2CA4
SCHEMBL11331361 0.78 CA2 (0.62) CA12CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4243584-A Monoazo dyestuffs containing diazo component substituted by disulfimide and trifluoromethyl groups BAYER AKTIENGESELLSCHAFT (DE) 1981-01-06 US disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4159265-A Phenylazopyrazolo dyestuffs including disulfimide substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-06-26 US disclosed
US-4060521-A POLYAMIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed