Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258847 | 0.82 | IGF1R (0.53) | KMT2ATSHRHTTMEN1L3MBTL1 | |
| SCHEMBL22997538 | 0.80 | KMT2A (0.45) | KMT2AMEN1L3MBTL1TRPA1KDM4E | |
| SCHEMBL29654161 | 0.80 | KMT2A (0.45) | KMT2AMEN1L3MBTL1TRPA1KDM4E | |
| SCHEMBL15235464 | 0.80 | KMT2A (0.45) | KMT2AMEN1L3MBTL1TRPA1KDM4E | |
| SCHEMBL353599 | 0.80 | KMT2A (0.45) | KMT2AMEN1L3MBTL1TRPA1KDM4E | |
| SCHEMBL7456002 | 0.79 | KMT2A (0.44) | KMT2AMEN1L3MBTL1TRPA1KDM4E | |
| SCHEMBL803704 | 0.79 | ACHE (0.55) | KMT2AL3MBTL1KDM4EMAPTRAB9A | |
| SCHEMBL2262233 | 0.79 | KMT2A (0.44) | KMT2AMEN1L3MBTL1TRPA1KDM4E | |
| SCHEMBL2817021 | 0.79 | ACHE (0.55) | KMT2AL3MBTL1KDM4EMAPTRAB9A | |
| SCHEMBL2853625 | 0.79 | ACHE (0.55) | KMT2AL3MBTL1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244880-A | Anthracycline synthesis | UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1981-01-13 | — | — | US | claimed |