S-Ethyl Dipropylcarbamothioate

S-Ethyl Dipropylcarbamothioate

SCHEMBL11327263

CCCN(CCC)C(=O)SCC.NC(O)=S

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.77
MAPK1 P28482 1/20 0.77
CA12 O43570 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
CA1 P00915 2/20 0.40
ALDH1A1 P00352 6/20 0.37
HPGD P15428 1/20 0.37
ALDH2 P05091 2/20 0.34
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.32
CYP1A2 P05177 3/20 0.32
CYP2D6 P10635 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
S-Ethyl Dipropylcarbamothioate SCHEMBL66482 0.88 TSHR (1.00) TSHRMAPK1CA12CA2CA9
S-Ethyl Dipropylcarbamothioate SCHEMBL8541416 0.88 TSHR (1.00) TSHRMAPK1CA12CA2CA9
Vernolate SCHEMBL10749396 0.87 TSHR (0.57) TSHRMAPK1CA12CA2CA9
S-Ethyl Dipropylcarbamothioate SCHEMBL8074575 0.86 TSHR (0.80) TSHRMAPK1CA12CA2CA9
S-Ethyl Dipropylcarbamothioate SCHEMBL11347969 0.86 TSHR (0.95) TSHRMAPK1CA12CA2CA9
SCHEMBL11814114 0.80 TSHR (0.83) TSHRMAPK1CA12CA2CA9
S-Ethyl Dipropylcarbamothioate SCHEMBL10793164 0.78 TSHR (0.80) TSHRMAPK1CA12CA2CA9
Butylate SCHEMBL10754959 0.78 TSHR (0.46) TSHRMAPK1CA12CA2CA9
S-Ethyl Dipropylcarbamothioate SCHEMBL7744541 0.77 TSHR (0.69) TSHRMAPK1CA12CA2CA9
Butylate SCHEMBL10835867 0.76 TSHR (0.62) TSHRMAPK1CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0054278-A1 Plant protecting agents for use during weed control, 2-(dichloromethyl)-3-phenyl-1,3-oxazolidine and 2-(dichloromethyl)-3-allyl-1,3-oxazolidine, and method for the preparation of the compounds comprised in said agents as antidotes, or of the latter mentioned compounds MAGYAR TUDOMANYOS AKADEMIA KÖZP KEMIAI KUTATO INTEZET (HU) 1982-06-23 EP disclosed