Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| S-Ethyl Dipropylcarbamothioate SCHEMBL8541416 | 0.83 | TSHR (1.00) | TSHRMAPK1TP53SMN1; SMN2MEN1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL66482 | 0.83 | TSHR (1.00) | TSHRMAPK1TP53SMN1; SMN2MEN1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL11347969 | 0.81 | TSHR (0.95) | TSHRMAPK1TP53SMN1; SMN2MEN1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL11327263 | 0.77 | TSHR (0.77) | TSHRMAPK1TP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL11814114 | 0.76 | TSHR (0.83) | TSHRMAPK1TP53MEN1KMT2A | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL10793164 | 0.74 | TSHR (0.80) | TSHRMAPK1TP53SMN1; SMN2MEN1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL8074575 | 0.74 | TSHR (0.80) | TSHRMAPK1TP53SMN1; SMN2MEN1 | |
| Pyridine SCHEMBL7744539 | 0.72 | TP53 (0.37) | TSHRMAPK1TP53SMN1; SMN2L3MBTL1 | |
| Butylate SCHEMBL8466988 | 0.71 | TSHR (0.74) | TSHRMAPK1TP53MEN1KMT2A | |
| SCHEMBL9799561 | 0.71 | TSHR (0.75) | TSHRMAPK1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037528-A4 | AGRICULTURAL ADJUVANT | COGNIS CORP (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1037528-A1 | AGRICULTURAL ADJUVANT | Cognis Corporation (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029171-A1 | AGRICULTURAL ADJUVANT | COGNIS CORPORATION (US) | 1999-06-17 | — | — | WO | disclosed |