Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928868 | 0.82 | CHRNB4 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL6928871 | 0.82 | CHRNB4 (0.50) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL6591943 | 0.75 | CHRNB2 (0.42) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL12676513 | 0.73 | POLB (0.49) | POLBGFERKMT2A | |
| SCHEMBL1409682 | 0.73 | POLB (0.71) | POLBDDB1CRBNLMNAALDH1A1 | |
| SCHEMBL13554974 | 0.70 | POLB (0.57) | POLBDDB1CRBNLMNAALDH1A1 | |
| SCHEMBL19831310 | 0.70 | CYP3A4 (0.55) | POLBALDH1A1GAAMAPTKMT2A | |
| SCHEMBL14062185 | 0.70 | RAD52 (0.53) | ALDH1A1GFERKMT2ARAB9A | |
| SCHEMBL3563193 | 0.69 | CHRNB2 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL11031223 | 0.69 | SMN1; SMN2 (0.46) | LMNAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247546-A | Phosphonylureidobenzene derivatives and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |
| EP-0002723-B1 | PHOSPHONYL-UREIDO-BENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION IN DRUGS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| EP-0002723-A1 | Phosphonyl-ureido-benzene derivatives, process for their preparation and their application in drugs | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |