Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.49 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023358 | 0.88 | SMN1; SMN2 (0.55) | ESR1ESR2MAPK1HTTKDM4E | |
| SCHEMBL8011384 | 0.85 | KDM4E (0.63) | ESR1ESR2MAPK1HTTGRIA1 | |
| SCHEMBL8025797 | 0.82 | HTT (0.54) | ESR1ESR2MAPK1HTTGRIA1 | |
| SCHEMBL11314713 | 0.82 | KDM4E (0.54) | MAPK1HTTKDM4EGAARECQL | |
| SCHEMBL28724218 | 0.82 | GAA (0.49) | ESR1ESR2MAPK1GRIA1CACNG8 | |
| SCHEMBL29445662 | 0.82 | GAA (0.49) | ESR1ESR2MAPK1GRIA1CACNG8 | |
| SCHEMBL24141136 | 0.82 | RECQL (0.48) | ESR1ESR2MAPK1HTTGRIA1 | |
| SCHEMBL3257779 | 0.81 | ESR2 (0.66) | ESR1ESR2MAPK1HTTGRIA1 | |
| SCHEMBL29351258 | 0.81 | ESR2 (0.66) | ESR1ESR2MAPK1HTTGRIA1 | |
| SCHEMBL64508 | 0.81 | ESR2 (0.66) | ESR1ESR2MAPK1HTTGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256626-A | 2-BENZIMIDAZOLYL-, 2-BENZOTHIAZOLYL-, OR 2-INDOLYL-PHENYL DERIVATIVES LINKED TO A 2-HYDROXYBENZOPHENONE | EASTMAN KODAK COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4174321-A | POLYMERIC MOLDING MATERIALS | EASTMAN KODAK COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4127501-A | BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4115348-A | DEGRADATION INHIBITORS | EASTMAN KODAK COMPANY (US) | 1978-09-19 | — | — | US | disclosed |