Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311250 | 0.94 | MEN1 (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30472181 | 0.94 | MEN1 (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16689153 | 0.87 | SMN1; SMN2 (0.59) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2245507 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11525939 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11328183 | 0.82 | ESR1 (0.57) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13311159 | 0.81 | MEN1 (0.71) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18758151 | 0.81 | MEN1 (0.58) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18758153 | 0.80 | MEN1 (0.61) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL24140817 | 0.78 | SMN1; SMN2 (0.49) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256626-A | 2-BENZIMIDAZOLYL-, 2-BENZOTHIAZOLYL-, OR 2-INDOLYL-PHENYL DERIVATIVES LINKED TO A 2-HYDROXYBENZOPHENONE | EASTMAN KODAK COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4115348-A | DEGRADATION INHIBITORS | EASTMAN KODAK COMPANY (US) | 1978-09-19 | — | — | US | disclosed |