Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341555 | 0.82 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL11325544 | 0.80 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2462636 | 0.77 | KDM4E (0.48) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL12255347 | 0.74 | AKR1C2 (0.50) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2462946 | 0.72 | KDM4E (0.51) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL4916175 | 0.71 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL11331442 | 0.70 | KDM4E (0.56) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL6291091 | 0.70 | KDM4E (0.68) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2003508 | 0.69 | AKR1C2 (0.53) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2466040 | 0.69 | KDM4E (0.55) | KDM4EMAPTGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302589-A | ANTIPSYCHOTIC | AMERICAN CYANAMID COMPANY (US) | 1981-11-24 | — | — | US | disclosed |