Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341555 | 0.83 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL11328489 | 0.80 | KDM4E (0.47) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL598456 | 0.79 | KDM4E (0.59) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL3566658 | 0.75 | AKR1C2 (0.53) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL11331442 | 0.73 | KDM4E (0.56) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2462946 | 0.72 | KDM4E (0.51) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL2009406 | 0.72 | KDM4E (0.60) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL13002847 | 0.72 | THRB (0.38) | KDM4EMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL4560886 | 0.71 | CYP1A2 (0.56) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL3342092 | 0.71 | CYP1A2 (0.49) | KDM4EMAPTGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302589-A | ANTIPSYCHOTIC | AMERICAN CYANAMID COMPANY (US) | 1981-11-24 | — | — | US | disclosed |