Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.77 |
| ▸ | CNR1 | P21554 | 1/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331126 | 1.00 | TDP1 (0.77) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11331132 | 1.00 | TDP1 (0.77) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9558539 | 0.91 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9862144 | 0.91 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8304052 | 0.91 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10982775 | 0.88 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10982768 | 0.88 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10982773 | 0.88 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL4991907 | 0.88 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1073320 | 0.88 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279920-A | 2,2-Dimethyl-3-(2-bromo-2-phenyl-vinyl)-cyclopropanecarboxylic acid 3-phenoxybenzyl esters and pesticidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | claimed |
| US-4279920-A | 2,2-Dimethyl-3-(2-bromo-2-phenyl-vinyl)-cyclopropanecarboxylic acid 3-phenoxybenzyl esters and pesticidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| US-4279920-A | 2,2-Dimethyl-3-(2-bromo-2-phenyl-vinyl)-cyclopropanecarboxylic acid 3-phenoxybenzyl esters and pesticidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| US-4279920-A | 2,2-Dimethyl-3-(2-bromo-2-phenyl-vinyl)-cyclopropanecarboxylic acid 3-phenoxybenzyl esters and pesticidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |