Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.82 |
| ▸ | CNR1 | P21554 | 1/20 | 0.82 |
| ▸ | ATM | Q13315 | 1/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862144 | 1.00 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9558539 | 1.00 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11302873 | 0.92 | TDP1 (0.73) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11331126 | 0.91 | TDP1 (0.77) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11331132 | 0.91 | TDP1 (0.77) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11328554 | 0.91 | TDP1 (0.77) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL4991907 | 0.90 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1073323 | 0.90 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1073320 | 0.90 | TDP1 (0.84) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL24089572 | 0.90 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555388-B1 | INSECTICIDAL, ACARICIDAL AND FUNGICIDAL AMINOPYRIMIDINES | DU PONT (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0513046-B1 | ARTHROPODICIDAL PYRAZOLINES, PYRAZOLIDINES AND HYDRAZINES | DU PONT (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0781768-A1 | Arthropodicidal anilides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0530264-B1 | ARTHROPODICIDAL TETRAHYDROPYRIDAZINES | DU PONT (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0565574-B1 | ARTHROPODICIDAL CARBOXANILIDES | DU PONT (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0365155-B1 | N-sulfenylated and N-acylated pyrazolines | DU PONT (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0286346-B1 | Insecticidal substituted indazoles | DU PONT (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0377304-B1 | Substituted semicarbazone arthropodicides | DU PONT (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5004822-A | Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-04-02 | — | — | US | disclosed |
| EP-0386892-A2 | Arthropodicidal tetrahydrobenzopyranopyrazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0322195-A1 | N-Formyl phosphonamidothioates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-28 | — | — | EP | disclosed |
| EP-0300692-A1 | Insecticidal pyrazolines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0223521-A2 | Insecticidal and acaricidal phenoxypyridinyl esters and intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-27 | — | — | EP | disclosed |
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |
| US-4464391-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-07 | — | — | US | disclosed |
| EP-0005826-A1 | Synergistic pyrethroid formulations and their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-12-12 | — | — | EP | disclosed |
| US-4171355-A | COMPRISING A CYCLOPROPYL CARBOXYLATE, A HETERO N-SUBSTITUTED THIOPHOSPHATE COMPOUND AND A HYDROXY-SUBSTITUTED BENZOPHENONE | ICI AUSTRALIA LIMITED (AU) | 1979-10-16 | — | — | US | disclosed |
| US-4100297-A | CHRYSANTHEMIC ACID DERIVATIVES | ROUSSEL UCLAF (FR) | 1978-07-11 | — | — | US | disclosed |