Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344701 | 0.93 | ALDH1A1 (0.59) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL9462903 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL8418411 | 0.82 | HRH3 (0.69) | FAAHHRH3MAPTKMT2AMEN1 | |
| SCHEMBL27543152 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL16669296 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL20440475 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL8369998 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HSP90AA1FAAHHRH3KMT2A | |
| SCHEMBL4627638 | 0.78 | HSP90AA1 (0.57) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL9672550 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSP90AA1CES1CES2FAAH | |
| SCHEMBL10456338 | 0.78 | HSP90AA1 (0.57) | ALDH1A1HSP90AA1CES1CES2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255308-A | A DISPERSION COMPRISING A BINDER OF A METHYL METHACRYLATE POLYMER, A DISPERSANT OF AN ACRYLIC TERPOLYMER, AND A GRAFT POLYMER OF THE TWO; FINISHES FOR CARS AND TRUCKS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-10 | — | — | US | disclosed |