Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711971 | 0.83 | KCNH2 (0.71) | SLC6A2SLC6A4POLBKCNH2HTR1A | |
| SCHEMBL8418048 | 0.79 | SIGMAR1 (0.60) | CDK4CCND1SIGMAR1HTR1ADRD2 | |
| SCHEMBL21273939 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4POLBKCNH2HTR1A | |
| SCHEMBL18301489 | 0.77 | KCNH2 (0.64) | SLC6A2SLC6A4POLBKCNH2HTR1A | |
| SCHEMBL11070192 | 0.77 | KCNH2 (0.64) | SLC6A2SLC6A4POLBKCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL11060044 | 0.77 | POLB (0.64) | SLC6A2SLC6A4POLBKCNH2HTR1A | |
| SCHEMBL3990185 | 0.77 | CDK4 (0.71) | CDK4CCND1SIGMAR1DRD2DRD4 | |
| SCHEMBL29780338 | 0.77 | CDK4 (0.71) | CDK4CCND1SIGMAR1DRD2DRD4 | |
| SCHEMBL11059996 | 0.76 | KCNH2 (0.67) | SLC6A2SLC6A4POLBKCNH2HTR1A | |
| SCHEMBL13711975 | 0.76 | KCNH2 (0.86) | SLC6A2SLC6A4POLBKCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302589-A | ANTIPSYCHOTIC | AMERICAN CYANAMID COMPANY (US) | 1981-11-24 | — | — | US | disclosed |