Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332226 | 0.89 | KDM4E (0.73) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5542189 | 0.87 | GAA (0.56) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4063835 | 0.85 | KDM4E (0.54) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22042899 | 0.85 | KDM4E (0.54) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13986779 | 0.85 | KDM4E (0.54) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30612631 | 0.85 | KDM4E (0.54) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12394367 | 0.85 | RAB9A (0.57) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23176649 | 0.84 | KDM4E (0.53) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5538663 | 0.84 | KDM4E (0.62) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23176644 | 0.82 | KDM4E (0.51) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |