Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332352 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL11327089 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL11324706 | 0.77 | TSHR (0.34) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL11332347 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL996687 | 0.74 | SMN1; SMN2 (0.92) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL15678743 | 0.74 | SMN1; SMN2 (0.92) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL7127609 | 0.74 | SMN1; SMN2 (0.92) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL9225132 | 0.74 | SMN1; SMN2 (0.92) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL17049376 | 0.74 | — | — | |
| SCHEMBL21142107 | 0.74 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259236-A | COLORFAST RED SHADES ON POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |