⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327089 | 0.82 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL9918912 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL5889866 | 0.79 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL27771469 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL7070990 | 0.78 | MAPK1 (0.38) | — | |
| SCHEMBL11324706 | 0.77 | TSHR (0.34) | — | |
| SCHEMBL14280940 | 0.76 | — | — | |
| SCHEMBL4556817 | 0.74 | — | — | |
| SCHEMBL14225602 | 0.74 | — | — | |
| SCHEMBL11328867 | 0.74 | SMN1; SMN2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3090007-B1 | CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS | COOPERVISION INT HOLDING CO LP (BB) | 2017-06-07 | — | — | EP | disclosed |
| US-9574038-B2 | Contact lenses made with HEMA-compatible polysiloxane macromers | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2017-02-21 | — | — | US | disclosed |
| US-20170008990-A1 | Contact Lenses Made With HEMA-Compatible Polysiloxane Macromers | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2017-01-12 | — | — | US | disclosed |
| EP-3090007-A1 | CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS | CooperVision International Holding Company, LP (BB) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015128636-A1 | CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2015-09-03 | — | — | WO | disclosed |