Methyl Alcohol

Methyl Alcohol

SCHEMBL11328895

CCc1cc([N+](=O)[O-])c(N)c([N+](=O)[O-])c1C.CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 6/20 0.38
TSHR P16473 4/20 0.38
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
RECQL P46063 1/20 0.38
LMNA P02545 2/20 0.37
GPR35 Q9HC97 1/20 0.37
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36
GRIN3A Q8TCU5 2/20 0.36
PDK1 Q15118 1/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11598706 0.97 POLB (0.49) POLBHTTALDH1A1TSHRCYP3A4
SCHEMBL1828689 0.79 TSHR (0.48) POLBALDH1A1TSHRCYP3A4CYP1A2
Nitric Acid SCHEMBL11648056 0.78 TSHR (0.44) POLBALDH1A1TSHRCYP3A4CYP1A2
SCHEMBL5203798 0.78 CYP1A2 (0.56) ALDH1A1TSHRCYP3A4CYP1A2RECQL
SCHEMBL11600578 0.77 GRIN2D (0.43) POLBHTTALDH1A1TSHRCYP3A4
Diethylamine SCHEMBL10937982 0.76 POLB (0.45) POLBHTTALDH1A1TSHRCYP3A4
Methyl Alcohol SCHEMBL11522592 0.76 L3MBTL1 (0.48) ALDH1A1CYP3A4CYP1A2LMNAGPR35
Methyl Alcohol SCHEMBL11331926 0.75 L3MBTL1 (0.47) HTTALDH1A1CYP3A4CYP1A2LMNA
SCHEMBL6897084 0.74 CYP1A2 (0.45) POLBHTTALDH1A1TSHRCYP3A4
SCHEMBL11328888 0.74 POLB (0.42) POLBHTTALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297127-A PREEMERGENCE HERBICIDES AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed
US-4251264-A 4-CYANO SUBSTITUTED AMERICAN CYANAMID COMPANY (US) 1981-02-17 US disclosed
US-4166908-A SELECTIVE PREEMERGENT ACTIVITY AMERICAN CYANAMID COMPANY (US) 1979-09-04 US disclosed
US-4165231-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1979-08-21 US disclosed
US-4124639-A N-alkoxyalkyl-2,6-dinitroaniline herbicides AMERICA CYANAMID COMPANY (US) 1978-11-07 US disclosed
US-4101582-A 2,6-Dinitroaniline herbicides AMERICAN CYANAMID COMPANY (US) 1978-07-18 US disclosed