Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042996 | 0.87 | GAA (0.59) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL5401038 | 0.87 | GAA (0.59) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL5759355 | 0.87 | GAA (0.59) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL30612619 | 0.87 | GAA (0.59) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL5396501 | 0.87 | GAA (0.59) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL4905806 | 0.84 | LOXL2 (0.64) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL27511631 | 0.84 | GAA (0.56) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL11336489 | 0.83 | AKR1B1 (0.61) | GAAL3MBTL1LIPGFAAHAAK1 | |
| SCHEMBL30358383 | 0.83 | GAA (0.55) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 | |
| SCHEMBL28318401 | 0.83 | GAA (0.55) | GAAL3MBTL1LIPGFAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |