Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324520 | 0.84 | HSD17B10 (0.50) | RAF1BRAFHSD17B10NPC1POLB | |
| SCHEMBL11331088 | 0.81 | GAA (0.58) | GAAHSD17B10POLBRAB9ATSHR | |
| SCHEMBL11336489 | 0.79 | AKR1B1 (0.61) | GAAAKR1B1NR4A1NR4A2NR4A3 | |
| SCHEMBL31614347 | 0.78 | NPC1 (0.61) | GAAAKR1B1NR4A1NR4A2NR4A3 | |
| SCHEMBL3112570 | 0.78 | NPC1 (0.61) | GAAAKR1B1NR4A1NR4A2NR4A3 | |
| Water SCHEMBL21626175 | 0.76 | NPC1 (0.59) | GAAAKR1B1NR4A1NR4A2NR4A3 | |
| SCHEMBL22371424 | 0.76 | GAA (0.57) | GAAAKR1B1NR4A1NR4A2NR4A3 | |
| SCHEMBL9073764 | 0.76 | GAA (0.61) | GAAHSD17B10NPC1POLBRAB9A | |
| SCHEMBL9074105 | 0.76 | AKR1B1 (0.58) | GAAHSD17B10AKR1B1NPC1POLB | |
| SCHEMBL11199551 | 0.76 | RAB9A (0.58) | GAAHSD17B10AKR1B1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |
| US-3985763-A | DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |