Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCLC | P48506 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329762 | 0.87 | CHRM1 (0.46) | GCLCCA2MAPK1FOLH1SLC1A3 | |
| SCHEMBL10440190 | 0.85 | FOLH1 (0.47) | FOLH1GRM3NAALAD2TDP1 | |
| SCHEMBL11343039 | 0.80 | CPT2 (0.35) | FOLH1CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL11344891 | 0.80 | CYP2D6 (0.31) | CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL8635672 | 0.79 | CYP1A2 (0.35) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL870763 | 0.76 | TSHR (0.39) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL11339953 | 0.76 | TSHR (0.33) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL22770 | 0.76 | FOLH1 (0.44) | FOLH1NAALAD2TSHRTDP1 | |
| SCHEMBL5691553 | 0.75 | ALDH1A1 (0.42) | CYP2D6TSHRCYP2C19HIF1ACHRM1 | |
| SCHEMBL11346356 | 0.75 | TSHR (0.33) | FOLH1CYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252857-A | Flameproofing substrate | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| US-4133872-A | Compositions for preparation of aqueous solutions of salts of lower valence 99 technetium | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-01-09 | — | — | US | disclosed |
| US-4086334-A | A CALCITONIN AND AN ADJUVANT CONTAINING CARBOXY AND/OR PHOSPHONO GROUPS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) | 1978-04-25 | — | — | US | disclosed |
| US-3962433-A | Method of treatment of calcium disorders using phosphonoalkane-polycarboxylic acids | HENKEL & CIE G.M.B.H. (DT) | 1976-06-08 | — | — | US | disclosed |