Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324582 | 0.83 | ADRB2 (0.51) | ADRB2ADRB1ADRB3CYP2D6 | |
| Hydrochloric Acid SCHEMBL11313818 | 0.82 | ADRB2 (0.50) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL11313507 | 0.81 | ADRB2 (0.58) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL11462026 | 0.78 | TSHR (0.52) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL11329600 | 0.73 | CYP2D6 (0.46) | CYP2D6 | |
| SCHEMBL8266174 | 0.69 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL7367812 | 0.69 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP2D6 | |
| Drobuline SCHEMBL120552 | 0.69 | ADRB2 (0.56) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL10693023 | 0.69 | ADRB2 (0.59) | ADRB2ADRB1ADRB3CYP2D6 | |
| Acetamide SCHEMBL5800005 | 0.69 | ADRB2 (0.83) | ADRB2ADRB1ADRB3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308399-A | O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-12-29 | — | — | US | claimed |