Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329640 | 0.86 | TSHR (0.49) | TSHRTDP1CES2CES1RORC | |
| SCHEMBL309038 | 0.83 | TSHR (0.64) | TSHRTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL28011591 | 0.82 | TSHR (0.59) | TSHRTDP1CES2CES1MEN1 | |
| SCHEMBL27827942 | 0.82 | TSHR (0.62) | TSHRTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL27623015 | 0.79 | HSP90AA1 (0.54) | TSHRTDP1CES2MEN1KMT2A | |
| Acetic Acid SCHEMBL11593607 | 0.79 | TSHR (0.62) | TSHRTDP1CES2CES1MEN1 | |
| Benzoic Acid SCHEMBL27636821 | 0.78 | TSHR (0.67) | TSHRTDP1CES2CES1MEN1 | |
| SCHEMBL28282548 | 0.77 | TDP1 (0.66) | TSHRTDP1CES2CES1MAPT | |
| Dinitrophenylene SCHEMBL17418136 | 0.77 | TSHR (0.63) | TSHRTDP1CES2CES1MAPT | |
| SCHEMBL29047909 | 0.77 | HSD17B10 (0.62) | TSHRTDP1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306103-A | Process for the manufacture of 1,3,5-trichlorobenzene | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |