Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | DNA2 | P51530 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827942 | 0.98 | TSHR (0.62) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL7086897 | 0.87 | TSHR (0.50) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL27287737 | 0.86 | TSHR (0.57) | TSHRDNA2CASP6CTDSP1TDP1 | |
| SCHEMBL1767333 | 0.85 | TSHR (0.50) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL308476 | 0.84 | TSHR (0.49) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3910666 | 0.84 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29488320 | 0.84 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11329635 | 0.83 | TSHR (0.54) | TSHRCTDSP1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8263377 | 0.83 | TSHR (0.57) | TSHRDNA2CASP6CTDSP1ALDH1A1 | |
| SCHEMBL8065104 | 0.83 | TDP1 (0.57) | TSHRCASP6TDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| CN-116143628-B | Preparation method of nitrobenzamide | 南通泰禾化工股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-115594592-B | Preparation method and application of 2-chloro-3-nitrobenzoic acid | 江西天宇化工有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-116143628-A | Preparation method of nitrobenzamide | 南通泰禾化工股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-115594592-A | Preparation method and application of 2-chloro-3-nitrobenzoic acid | 江西天宇化工有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-106835327-B | A kind of preparation method of the photochromic nano micron fibre of multiple bases | 天津工业大学 | 2019-07-26 | — | — | CN | claimed |
| CN-109535081-A | A kind of preparation method of Flubendazole impurity E | 江苏宝众宝达药业有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-109448993-A | Electrolyte of aluminum electrolytic capacitor and preparation method thereof | 广州金立电子有限公司 | 2019-03-08 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| EP-0661388-A1 | Chemical etchant for palladium | AT&T Corp. (US) | 1995-07-05 | — | — | EP | claimed |
| US-5380400-A | From copper substrate, oxidant and corrosion inhibitor | AT&T CORP. (US) | 1995-01-10 | — | — | US | claimed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | claimed |
| US-RE34272-E | Oxalic acid, a thiocyanate salt, and a nitrobenzenesulfonate salt | REM CHEMICALS, INC. (US) | 1993-06-08 | — | — | US | claimed |
| EP-0395815-B1 | METHOD AND COMPOSITION FOR REFINEMENT OF METAL SURFACES | REM CHEMICALS, INC. (US) | 1993-06-02 | — | — | EP | claimed |
| EP-0395815-A1 | Method and composition for refinement of metal surfaces | REM CHEMICALS, INC. (US) | 1990-11-07 | — | — | EP | claimed |
| US-4906327-A | Method and composition for refinement of metal surfaces | REM CHEMICALS, INC. (US) | 1990-03-06 | — | — | US | claimed |
| US-4866204-A | OXIDATION WITH METAL ACETYLACETONATES, PORPYRINS OR PHTHALOCYANINE CATALYSTS | NOBEL CHEMICALS AB (SE) | 1989-09-12 | — | — | US | claimed |
| US-4548791-A | Thallium-containing composition for stripping palladium | AMERICAN CHEMICAL & REFINING COMPANY, INC. (US) | 1985-10-22 | — | — | US | claimed |
| US-3935005-A | Composition and method for stripping gold and silver | AMERICAN CHEMICAL & REFINING COMPANY, INCORPORATED (US) | 1976-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | TSHR 1605/4885DNA2 4120/4885CASP6 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.