SCHEMBL1132980

SCHEMBL1132980

C=C(C)C(=O)OC(CCCCC)CC[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
FAAH O00519 1/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28517612 0.97 TSHR (0.45) TSHRFAAHTHRB
SCHEMBL28515897 0.96 TSHR (0.48) TSHRFAAH
SCHEMBL28508981 0.95 TSHR (0.42) TSHRFAAHTHRB
SCHEMBL1133008 0.93 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL1132758 0.90 TSHR (0.40) TSHRFAAHTHRB
SCHEMBL31484376 0.86 TSHR (0.37) TSHRTHRB
SCHEMBL1132962 0.86 TSHR (0.41) TSHRFAAHALDH1A1
SCHEMBL7876250 0.85 TSHR (0.43) TSHRFAAH
SCHEMBL7878019 0.85 TSHR (0.43) TSHRFAAH
SCHEMBL6832092 0.85 TSHR (0.43) TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP claimed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US claimed
US-20110046325-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF, AND A CATALYST COMPRISING THE CATALYST COMPONENT CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-24 US claimed
EP-2287212-A1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component China Petroleum & Chemical Corporation (CN) 2011-02-23 EP claimed
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP disclosed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US disclosed
US-20110046325-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF, AND A CATALYST COMPRISING THE CATALYST COMPONENT CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-24 US disclosed
EP-2287212-A1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component China Petroleum & Chemical Corporation (CN) 2011-02-23 EP disclosed