SCHEMBL7878019

SCHEMBL7878019

C=C(C)C(=O)OC(CCCCCCCCC)CC[Si](OC)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
GLS2 Q9UI32 3/20 0.37
LMNA P02545 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
FAAH O00519 1/20 0.35
GPR84 Q9NQS5 3/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
FFAR1 O14842 1/20 0.33
ABCB1 P08183 1/20 0.32
EPHX1 P07099 1/20 0.32
LCK P06239 1/20 0.32
PPARD Q03181 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
CNR1 P21554 1/20 0.32
DAGLA Q9Y4D2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7876250 1.00 TSHR (0.43) TSHRGLS2LMNAZDHHC7FAAH
SCHEMBL6832092 1.00 TSHR (0.43) TSHRGLS2LMNAZDHHC7FAAH
SCHEMBL7878009 1.00 TSHR (0.43) TSHRGLS2LMNAZDHHC7FAAH
SCHEMBL1132962 0.99 TSHR (0.41) TSHRGLS2LMNAZDHHC7FAAH
SCHEMBL31484377 0.94 TSHR (0.38) TSHRGLS2LMNA
SCHEMBL5954825 0.89 TSHR (0.38) TSHRGLS2LMNA
SCHEMBL1133157 0.88 ALDH1A1 (0.38) TSHR
SCHEMBL3904814 0.88 TSHR (0.42) TSHRGLS2ZDHHC7FAAHGPR84
SCHEMBL15535954 0.87 TSHR (0.41) TSHRGLS2ZDHHC7FAAHGPR84
SCHEMBL1158372 0.87 ALDH1A1 (0.35) TSHRGLS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
EP-3219736-B1 WATER-BASED RESIN DISPERSION AND COATING MATERIAL DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2020-11-25 EP disclosed
EP-3219775-B1 ADHESIVE AGENT COMPOSITION AND ADHESIVE AGENT DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2020-08-19 EP disclosed
US-10457754-B2 Water-based resin dispersion and coating material DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2019-10-29 US disclosed
US-10280341-B2 Adhesive agent composition and adhesive agent DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2019-05-07 US disclosed
US-20170327602-A1 WATER-BASED RESIN DISPERSION AND COATING MATERIAL DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2017-11-16 US disclosed
US-20170306192-A1 ADHESIVE AGENT COMPOSITION AND ADHESIVE AGENT DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2017-10-26 US disclosed
EP-3219736-A1 WATER-BASED RESIN DISPERSION AND COATING MATERIAL Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2017-09-20 EP disclosed
EP-3219775-A1 ADHESIVE AGENT COMPOSITION AND ADHESIVE AGENT Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2017-09-20 EP disclosed
US-6329461-B1 SUBJECTNG AQUEOUS EMULSION CONTAINING POLYALKOXYPOLYSILOXANE AN UNSATURATED MONOMER AND EMULSIFIER TO POLYMERIZATION IN PRESENCE OF POLYMERIZATION INITIATOR NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-12-11 US disclosed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP disclosed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US disclosed