Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Formic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL11329899 | 1.00 | — | — | |
| Formic Acid SCHEMBL2303 | 0.94 | — | — | |
| Formic Acid SCHEMBL2511100 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL1064783 | 0.94 | — | — | |
| Formic Acid SCHEMBL811681 | 0.94 | — | — | |
| Formic Acid SCHEMBL424643 | 0.94 | — | — | |
| Formic Acid SCHEMBL1545869 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL18112628 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL394887 | 0.94 | ALDH1A1 (0.33) | — | |
| Formic Acid SCHEMBL83909 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302578-A | 7B-(D-5-AMINO-5-CARBOXYVALERAMIDO)-7-METHOXY-3-CEPHEM-4-CARBOXY ACIDS | MERCK & CO., INC. (US) | 1981-11-24 | — | — | US | disclosed |
| US-4036696-A | 7B-(D-5-AMINO-5-CARBOXYVALERAMIDO)-3-(CARBAMOYLOXYMETHYL)-7 -METHOXY-3-CEPHEM-4-CARBOXYLIC ACID | MERCK & CO., INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-4017487-A | EFFECTIVE AGAINST GRAMPOSITIVE AND GRAMNEGATIVE BACTERIA | MERCK & CO., INC. (US) | 1977-04-12 | — | — | US | disclosed |
| US-3985742-A | BY FERMENTATION OR SYNTHETIC MEANS | MERCK & CO., INC. (US) | 1976-10-12 | — | — | US | disclosed |