Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312242 | 1.00 | NAAA (0.52) | NAAAEGFRSYKALOX5PTGS2 | |
| SCHEMBL3227231 | 0.86 | KAT8 (0.57) | NAAAALOX5PTGS2KAT8HSP90AA1 | |
| SCHEMBL27374196 | 0.86 | KAT8 (0.57) | NAAAALOX5PTGS2KAT8HSP90AA1 | |
| SCHEMBL3213862 | 0.85 | KAT8 (0.56) | NAAAALOX5PTGS2KAT8HSP90AA1 | |
| SCHEMBL3213853 | 0.84 | KAT8 (0.42) | NAAAKAT8HSP90AA1HSP90AB1 | |
| SCHEMBL11315020 | 0.83 | GAA (0.54) | NAAAALOX5HSP90AA1HSP90AB1ADRB2 | |
| SCHEMBL23920298 | 0.78 | HSD17B10 (0.46) | PTGS2ADRB2ADRB1ADRB3 | |
| SCHEMBL1835127 | 0.77 | USP2 (0.42) | — | |
| SCHEMBL24592686 | 0.77 | ESR1 (0.46) | — | |
| SCHEMBL1836601 | 0.77 | USP2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |