Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513110 | 0.69 | — | — | |
| SCHEMBL8851340 | 0.69 | — | — | |
| SCHEMBL17787243 | 0.69 | HSD17B10 (0.56) | HSD17B10TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL28744268 | 0.68 | AHR (0.43) | ALDH1A1LMNASLC2A1AHR | |
| SCHEMBL29788814 | 0.68 | AHR (0.43) | ALDH1A1LMNASLC2A1AHR | |
| SCHEMBL2368215 | 0.67 | CYP3A4 (0.55) | HSD17B10TSHRCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL6520911 | 0.67 | HSD17B10 (0.54) | HSD17B10TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL6516471 | 0.67 | HSD17B10 (0.54) | HSD17B10TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL6520906 | 0.67 | HSD17B10 (0.54) | HSD17B10TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL11141475 | 0.67 | ESR1 (0.61) | HSD17B10TSHRCYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299966-A | Process for the preparation of 4,4',7,7'-tetrachlorthioindigo in pigment form | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | claimed |
| EP-0018008-A2 | Process for the production of glazing-pigment forms of 4,4',7,7'-tetrachlorothio indigo | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |