SCHEMBL17787243

SCHEMBL17787243

Oc1ccc(O)c2cc(Cl)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.56
TSHR P16473 2/20 0.56
ALDH1A1 P00352 3/20 0.52
HPGD P15428 3/20 0.52
ALOX15 P16050 3/20 0.52
ALOX12 P18054 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK1 P28482 2/20 0.52
IDO1 P14902 6/20 0.50
CYP3A4 P08684 3/20 0.50
HIF1A Q16665 3/20 0.50
MEN1 O00255 3/20 0.50
HTT P42858 3/20 0.50
KMT2A Q03164 3/20 0.50
HSP90AA1 P07900 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
SLC22A1 O15245 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5363776 0.88 HSD17B10 (0.56) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL25408639 0.84 HSD17B10 (0.46) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL15961769 0.78 HSD17B10 (0.50) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL6242615 0.78 HSD17B10 (0.62) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL31093991 0.78 HSD17B10 (0.62) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL29405140 0.75
SCHEMBL70036 0.75
SCHEMBL2617539 0.73 ALDH1A1 (0.40) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL11281349 0.73 IDO1 (0.56) HSD17B10TSHRALDH1A1HPGDALOX15
SCHEMBL29507259 0.73 IDO1 (0.56) HSD17B10TSHRALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353257-B2 Cationically cross-linkable/polymerizable organic resin composition comprising an iodonium borate and having an acceptable smell BLUESTAR SILICONES FRANCE SAS (FR) 2016-05-31 US disclosed
US-9353257-B2 Cationically cross-linkable/polymerizable organic resin composition comprising an iodonium borate and having an acceptable smell BLUESTAR SILICONES FRANCE SAS (FR) 2016-05-31 US disclosed