Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330590 | 1.00 | CTSS (0.49) | CTSSCTSKMIFPPARAPPARG | |
| SCHEMBL57550 | 0.88 | CTSS (0.49) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL58394 | 0.88 | CTSS (0.49) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL5024738 | 0.88 | CTSS (0.49) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL3163458 | 0.87 | PPARA (0.52) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL6674296 | 0.87 | CTSS (0.50) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL2797717 | 0.87 | PPARA (0.48) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL6674294 | 0.87 | CTSS (0.50) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL2797710 | 0.87 | PPARA (0.48) | CTSSCTSKPPARAPPARGCTSL | |
| SCHEMBL9963920 | 0.87 | CTSS (0.50) | CTSSCTSKPPARAPPARGCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |