Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671057 | 1.00 | DUSP3 (0.61) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL11320066 | 1.00 | DUSP3 (0.61) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL11335819 | 1.00 | DUSP3 (0.61) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL12748845 | 0.85 | DUSP3 (0.46) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL7559836 | 0.80 | ALDH1A1 (0.59) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL14946835 | 0.77 | DUSP3 (0.40) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL12768326 | 0.76 | DUSP3 (1.00) | DUSP3LMNAMAPTKMT2AMEN1 | |
| SCHEMBL10671639 | 0.75 | TNF (0.46) | DUSP3ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL3020106 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL16356280 | 0.72 | ALDH1A1 (0.39) | DUSP3ALDH1A1LMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273674-A | HALOGENATED PHTHALIMIDES | GENERAL ELECTRIC COMPANY (US) | 1981-06-16 | — | — | US | claimed |
| US-4204428-A | Thermal detection system for failure in electrical apparatus and thermal detecting paint compositions | GENERAL ELECTRIC COMPANY (US) | 1980-05-27 | — | — | US | claimed |