SCHEMBL11330876

SCHEMBL11330876

C=CC(=O)OC(=O)/C=C/C

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.37
HPGD P15428 1/20 0.35
ALDH1A1 P00352 7/20 0.35
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14620010 1.00 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL297108 1.00 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
Acetic Acid SCHEMBL779040 0.93 ALDH1A1 (0.36) TSHRHPGDALDH1A1TP53HIF1A
Methacrylic Acid SCHEMBL775560 0.88 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL25405174 0.87 HCAR2 (0.40) TSHRALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL16503 0.87 HCAR2 (0.40) TSHRALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL16505 0.87 HCAR2 (0.40) TSHRALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL25405178 0.87 HCAR2 (0.40) TSHRALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL16504 0.87 HCAR2 (0.40) TSHRALDH1A1KEAP1NFE2L2HCAR2
SCHEMBL29159369 0.84 TSHR (0.33) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655742-B Acrylic polymer coagulum 株式会社可乐丽 2023-08-29 CN disclosed
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
CN-105916950-B Rosin ester and composition thereof 阿利桑那化学公司 2019-12-17 CN disclosed
US-4281207-A CROSSLINKING POLYMERS USEFUL IN RELIEF IMAGES, PHOTORESISTS, AND LITHOGRAPHIC PLATES EASTMAN KODAK COMPANY (US) 1981-07-28 US disclosed
US-4225689-A PHOTORESISTS, LITHOGRAPHIC PLATES, RELIF IMAGES EASTMAN KODAK COMPANY (US) 1980-09-30 US disclosed
US-4219614-A ACRYLIC COPOLYMERS AS CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1980-08-26 US disclosed