Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438264 | 0.97 | CYP19A1 (0.37) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11464503 | 0.77 | CYP19A1 (0.57) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11461581 | 0.76 | CYP19A1 (0.48) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11462948 | 0.75 | CYP11B1 (0.50) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11479501 | 0.75 | CYP19A1 (0.47) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11461962 | 0.75 | CYP19A1 (0.44) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11465917 | 0.75 | CYP19A1 (0.68) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11429930 | 0.73 | CYP19A1 (0.43) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11339515 | 0.71 | CYP26A1 (0.49) | CYP26A1CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11275821 | 0.70 | CYP17A1 (0.51) | CYP19A1CYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005250-B1 | HYDROXYPROPYL IMIDAZOLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BAYER AG (DE) | 1981-08-12 | — | — | EP | disclosed |
| EP-0011769-A1 | Hydroxyethyl azoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0005250-A2 | Hydroxypropyl imidazoles, their preparation and medicaments containing them | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |