Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965559 | 0.78 | CYP11B1 (0.57) | CYP19A1CYP11B1CYP11B2CYP17A1POLB | |
| SCHEMBL11275821 | 0.77 | CYP17A1 (0.51) | CYP19A1CYP11B1CYP11B2CYP17A1HPGD | |
| SCHEMBL7387804 | 0.75 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2CYP17A1CYP26A1 | |
| SCHEMBL11247883 | 0.74 | CYP17A1 (0.55) | CYP19A1CYP11B1CYP11B2CYP17A1POLB | |
| SCHEMBL11436593 | 0.74 | CYP26A1 (0.52) | CYP19A1CYP11B1CYP11B2CYP17A1CYP26A1 | |
| SCHEMBL11465747 | 0.73 | CYP19A1 (0.78) | CYP19A1CYP11B1CYP11B2CYP17A1POLB | |
| SCHEMBL11333155 | 0.73 | CYP26A1 (0.37) | CYP19A1CYP11B1CYP11B2CYP17A1CYP26A1 | |
| SCHEMBL11438264 | 0.73 | CYP19A1 (0.37) | CYP19A1CYP11B1CYP11B2CYP17A1CYP26A1 | |
| SCHEMBL11287252 | 0.71 | CYP17A1 (0.74) | CYP19A1CYP11B1CYP11B2CYP17A1HPGD | |
| SCHEMBL5382493 | 0.69 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2CYP17A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011769-A1 | Hydroxyethyl azoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |