Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657794 | 0.82 | TSHR (0.54) | TSHRLMNAALDH1A1TDP1PYCR1 | |
| SCHEMBL6046848 | 0.82 | TSHR (0.66) | TSHRLMNAALDH1A1TDP1PYCR1 | |
| SCHEMBL16064087 | 0.82 | TSHR (0.53) | TSHRLMNAALDH1A1TDP1PYCR1 | |
| SCHEMBL3126907 | 0.81 | LMNA (0.49) | TSHRLMNAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3411797 | 0.78 | TSHR (0.49) | TSHRLMNAALDH1A1TDP1PYCR1 | |
| Hydrochloric Acid SCHEMBL10867338 | 0.78 | TSHR (0.60) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL27999913 | 0.77 | TSHR (0.58) | TSHRLMNAALDH1A1TDP1PYCR1 | |
| SCHEMBL11366219 | 0.77 | TSHR (0.58) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL27999912 | 0.77 | TSHR (0.58) | TSHRLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL4657130 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1TDP1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243606-A | AZO DYE COUPLER INTERMEDIATES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-01-06 | — | — | US | disclosed |
| US-4218369-A | FOR DYEING POLYACRYLONITRILE | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-08-19 | — | — | US | disclosed |
| US-4010151-A | Water insoluble mono azo and disazo dyes containing cinnamonitrile group | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-03-01 | — | — | US | disclosed |
| US-4008213-A | WATER INSOLUBLE | UGINE KUHLMANN (FR) | 1977-02-15 | — | — | US | disclosed |