Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472586 | 0.98 | TSHR (0.44) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL30807815 | 0.98 | TSHR (0.44) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL11422863 | 0.90 | TSHR (0.39) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL10497156 | 0.80 | TSHR (0.44) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL11330429 | 0.79 | CYP3A4 (0.42) | TSHRALDH1A1CYP3A4TP53MEN1 | |
| SCHEMBL19191408 | 0.78 | KMT2A (0.36) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL10663959 | 0.78 | TSHR (0.43) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL14179811 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACASP1POLB | |
| SCHEMBL15629572 | 0.77 | CYP3A4 (0.48) | TSHRALDH1A1HSD17B10TDP1CYP3A4 | |
| SCHEMBL15305842 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CYP3A4TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |