Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329123 | 0.86 | KDM4E (0.48) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11336741 | 0.84 | KDM4E (0.49) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11325951 | 0.84 | AGPAT2 (0.44) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11330860 | 0.83 | KDM4E (0.47) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11328981 | 0.82 | KDM4E (0.43) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11324879 | 0.81 | RAB9A (0.53) | SMN1; SMN2NPC1RAB9AMAPTGAA | |
| SCHEMBL11321391 | 0.80 | HPGD (0.47) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9073764 | 0.78 | GAA (0.61) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11333951 | 0.78 | AGPAT2 (0.47) | HPGDKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11341446 | 0.77 | RAB9A (0.50) | HPGDKDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |