Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339198 | 0.84 | ALDH1A1 (0.73) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL11337642 | 0.83 | ALDH1A1 (0.71) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL2326315 | 0.83 | ALDH1A1 (1.00) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL2324818 | 0.82 | ALDH1A1 (0.70) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL11114941 | 0.81 | ALDH1A1 (0.62) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL22322825 | 0.81 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL11338836 | 0.80 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL11340045 | 0.80 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL11631291 | 0.79 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 | |
| SCHEMBL23093193 | 0.78 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1GAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4159375-A | 6- AND 7-Aryl-1,2,4-triazolo[4,3-b]-1,2,4-triazines | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |