Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17226294 | 0.77 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL7005368 | 0.77 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL8082747 | 0.76 | ESR1 (0.62) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL15854157 | 0.74 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL7615003 | 0.74 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL28682070 | 0.74 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL8757282 | 0.72 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL6029816 | 0.72 | HCAR2 (0.43) | ADRA2AADRA2BADRA2CTSHRCYP2D6 | |
| SCHEMBL704522 | 0.72 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CSLC6A2 | |
| SCHEMBL6030593 | 0.72 | HCAR2 (0.43) | ADRA2AADRA2BADRA2CTSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285887-A1 | BASIC STABILISATION SYSTEMS FOR EMULSION POLYMERISED RUBBERS | BASF SE (DE) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009138342-A1 | BASIC STABILISATION SYSTEMS FOR EMULSION POLYMERISED RUBBERS | BASF SE (DE) | 2009-11-19 | — | — | WO | disclosed |