Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106514 | 0.83 | ADRA2A (0.42) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL8082747 | 0.81 | ESR1 (0.62) | ESR1ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL705405 | 0.79 | GABRA1 (0.44) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL15854157 | 0.79 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL28682070 | 0.79 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL7615003 | 0.79 | ESR1 (0.54) | ESR1ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL1315151 | 0.78 | ESR1 (0.48) | ESR1ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL28670787 | 0.78 | ESR1 (0.44) | ESR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL8757282 | 0.77 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CACHE | |
| SCHEMBL7005368 | 0.77 | ESR1 (0.52) | ESR1ADRA2AADRA2BADRA2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181223-B | Low-gloss matte auxiliary agent, preparation method thereof and molded body | 铨盛聚碳科技股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110709437-B | Polyorganosiloxane-containing graft copolymer, thermoplastic resin composition, and molded article | 三菱化学株式会社 | 2022-07-05 | — | — | CN | disclosed |
| CN-109716544-B | Sealing material composition for LED | 日产化学株式会社 | 2021-11-09 | — | — | CN | disclosed |
| CN-109715680-B | Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions | 株式会社普利司通 | 2021-10-19 | — | — | CN | disclosed |
| EP-3133105-B1 | HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE | SHINETSU CHEMICAL CO (JP) | 2020-12-09 | — | — | EP | disclosed |
| CN-110709437-A | Polyorganosiloxane-containing graft copolymer, thermoplastic resin composition, and molded article | 三菱化学株式会社 | 2020-01-17 | — | — | CN | disclosed |
| US-9890251-B2 | Hydrosilyl-containing organopolysiloxane, making method, addition curable silicone composition, and semiconductor package | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-3133105-A1 | HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE | Shin-Etsu Chemical Co., Ltd. (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-20170029571-A1 | HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-02-02 | — | — | US | disclosed |
| EP-2914664-B1 | CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE | DOW CORNING TORAY CO LTD (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-8124239-B2 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8003736-B2 | Silicon-containing compound, curable composition and cured product | ADEKA CORPORATION (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20100179283-A1 | SILICON-CONTAINING COMPOUND, CURABLE COMPOSITION AND CURED PRODUCT | ADEKA CORPORATION (JP) | 2010-07-15 | — | — | US | disclosed |
| US-20100155121-A1 | SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME | FUJITSU LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7659357-B2 | Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed | FUJITSU LIMITED (JP) | 2010-02-09 | — | — | US | disclosed |
| EP-2141188-A1 | SILICON-CONTAINING COMPOUND, CURABLE COMPOSITION AND CURED PRODUCT | Adeka Corporation (JP) | 2010-01-06 | — | — | EP | disclosed |
| US-20070026689-A1 | Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same | FUJITSU LIMITED (JP) | 2007-02-01 | — | — | US | disclosed |
| US-6020448-A | N-[ω-(methyl),ω-(silyl)] alkyl-N-organocarboxamides, oligomeric and polycondensed Si-containing compounds thereof, processes for their preparation, and their use | HUELS AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| US-5554706-A | LOW TEMPERATURE LIQUID CRYSTALS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0695770-A1 | COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-02-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179283-A1 | SILICON-CONTAINING COMPOUND, CURABLE COMPOSITION AND CURED PRODUCT | H1-0, H1-10, H1-2 | ESR1 2892/4885ADRA2A 4199/4885ADRA2B 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.