Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154197 | 0.92 | RECQL (0.47) | THRATHRBLTB4RLTB4R2MAPT | |
| Sulfuric Acid SCHEMBL11075749 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL11756819 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL11219747 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL9420252 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL11221109 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL10872225 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL10597047 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL10596669 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT | |
| SCHEMBL11877604 | 0.90 | THRA (0.51) | THRATHRBLTB4RLTB4R2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296226-A | Vinyl polymer with acetylacetoxy groups, process for its manufacture and an agent obtained thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |