Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221242 | 0.81 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL29391624 | 0.81 | KMT2A (0.76) | KMT2AMEN1MAPK10GFERADRA2A | |
| Bromide SCHEMBL28368455 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL30947359 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL6175579 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL11133606 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL4243882 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL6175584 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL6574416 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A | |
| SCHEMBL3038944 | 0.79 | KMT2A (0.73) | KMT2AMEN1MAPK10GFERADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276297-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1981-06-30 | — | — | US | disclosed |
| US-4276297-A | ANTIULCER AGENTS | PFIZER INC. (US) | 1981-06-30 | — | — | US | disclosed |