Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057624 | 1.00 | DGKA (0.57) | DGKAHRH2HRH1DNM1GNAI3 | |
| SCHEMBL11337135 | 1.00 | DGKA (0.57) | DGKAHRH2HRH1DNM1GNAI3 | |
| SCHEMBL11712690 | 0.93 | HRH2 (0.60) | DGKAHRH2HRH1DNM1GNAI3 | |
| SCHEMBL11779963 | 0.93 | HRH2 (0.60) | DGKAHRH2HRH1DNM1GNAI3 | |
| SCHEMBL17401261 | 0.89 | DGKA (0.67) | DGKAHRH2HRH1DNM1PAM | |
| SCHEMBL11628693 | 0.89 | DGKA (0.67) | DGKAHRH2HRH1DNM1PAM | |
| SCHEMBL17401259 | 0.89 | DGKA (0.67) | DGKAHRH2HRH1DNM1PAM | |
| SCHEMBL23864897 | 0.85 | DGKA (0.61) | DGKAHRH2HRH1DNM1PAM | |
| SCHEMBL12120107 | 0.85 | DGKA (0.61) | DGKAHRH2HRH1DNM1PAM | |
| SCHEMBL12120105 | 0.85 | DGKA (0.61) | DGKAHRH2HRH1DNM1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243805-A | 3 Fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(bf) thiepins and method for the preparation thereof | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1981-01-06 | — | — | US | disclosed |