Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440796 | 0.90 | MEN1 (0.70) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL11094894 | 0.90 | MEN1 (0.70) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL3317902 | 0.90 | MEN1 (0.70) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29440795 | 0.90 | MEN1 (0.70) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL2045765 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29440790 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29742230 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL29918462 | 0.88 | KMT2A (0.79) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL11679799 | 0.87 | NPC1 (0.74) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL10340630 | 0.87 | KMT2A (0.67) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989498-B2 | Immunosuppressants; autoimmune disease; organs transplantation; antiinflammatory agents; viricides; antiproliferative agents; antitumor, anticancer agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-7989498-B2 | Immunosuppressants; autoimmune disease; organs transplantation; antiinflammatory agents; viricides; antiproliferative agents; antitumor, anticancer agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-7915255-B2 | Metabolism-modulating agents and uses therefor | VERVA PHARMACEUTICALS PTY LTD (AU) | 2011-03-29 | — | — | US | disclosed |
| US-7915255-B2 | Metabolism-modulating agents and uses therefor | VERVA PHARMACEUTICALS PTY LTD (AU) | 2011-03-29 | — | — | US | disclosed |
| US-4284704-A | Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt | EASTMAN KODAK COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| US-RE30267-E | SEMIPERMEABLE MEMBRANE, THIN FILM | EASTMAN KODAK COMPANY (US) | 1980-05-06 | — | — | US | disclosed |
| US-4066403-A | DECOMPOSITION, PERMEABLE BARRIERS | EASTMAN KODAK COMPANY (US) | 1978-01-03 | — | — | US | disclosed |