SCHEMBL2045765

SCHEMBL2045765

COc1ccccc1NC(=O)c1cc2ccccc2cc1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.79
MEN1 O00255 6/20 0.79
MAPT P10636 6/20 0.79
POLB P06746 5/20 0.79
KDM4E B2RXH2 2/20 0.79
MCL1 Q07820 1/20 0.79
NPSR1 Q6W5P4 1/20 0.79
NPC1 O15118 5/20 0.70
MAPK1 P28482 1/20 0.70
NOD2 Q9HC29 1/20 0.70
RAB9A P51151 7/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
TUBB4A P04350 1/20 0.64
TUBB P07437 1/20 0.64
TUBA3C P0DPH7 1/20 0.64
TUBA1B P68363 1/20 0.64
TUBA4A P68366 1/20 0.64
TUBB4B P68371 1/20 0.64
TUBB3 Q13509 1/20 0.64
TUBB2A Q13885 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742230 1.00 KMT2A (0.79) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL29918462 1.00 KMT2A (0.79) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL29440790 1.00 KMT2A (0.79) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL6577185 0.90 KMT2A (0.77) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL10815220 0.89 MAPT (0.65) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL12368274 0.89 MEN1 (0.65) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL6430894 0.89 MAPT (1.00) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL11094894 0.88 MEN1 (0.70) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL11337337 0.88 MEN1 (0.76) KMT2AMEN1MAPTPOLBKDM4E
SCHEMBL29440795 0.88 MEN1 (0.70) KMT2AMEN1MAPTPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085543-B Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2023-11-07 CN claimed
CN-116803941-A Low-carbon high-strength corrosion-resistant tubular pile and preparation method thereof 江苏诚意工程技术研究院有限公司 2023-09-26 CN claimed
CN-114179543-A Holographic self-repairing graphene liquid crystal modified polyurethane decorative film and preparation method and application thereof 深圳市深大极光科技有限公司 2022-03-15 CN claimed
CN-114085543-A Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2022-02-25 CN claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
CN-114085543-B Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2023-11-07 CN disclosed
CN-116803941-A Low-carbon high-strength corrosion-resistant tubular pile and preparation method thereof 江苏诚意工程技术研究院有限公司 2023-09-26 CN disclosed
CN-114179543-A Holographic self-repairing graphene liquid crystal modified polyurethane decorative film and preparation method and application thereof 深圳市深大极光科技有限公司 2022-03-15 CN disclosed
CN-114085543-A Application of quaternary ammonium salt derivative in preparation of red pigment, red pigment and preparation method 龙口联合化学股份有限公司 2022-02-25 CN disclosed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP disclosed
EP-3029109-B1 CROSSLINKING COMPOSITION EXHIBITING EXCELLENT STORAGE STABILITY OSAKA SODA CO LTD (JP) 2018-01-31 EP disclosed
US-20160222161-A1 CROSSLINKING COMPOSITION EXHIBITING EXCELLENT STORAGE STABILITY OSAKA SODA CO., LTD. (JP) 2016-08-04 US disclosed
US-4066403-A DECOMPOSITION, PERMEABLE BARRIERS EASTMAN KODAK COMPANY (US) 1978-01-03 US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 US disclosed
US-4058515-A Metallized phenyl-azo-naphthol compounds TOMS RIVER CHEMICAL CORPORATION (US) 1977-11-15 US disclosed
US-4057389-A Process for the printing with developing dyes HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-08 US disclosed
US-4035144-A Dyeing preparations containing boric acid for preparing water-insoluble azo dyestuffs on fiber HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed
US-3961884-A Process for dyeing textile material of polyester fiber/cellulose blends HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3947515-A Process for the preparation of pure, aromatic o-hydroxy-carboxylic acid aryl amides HOECHST AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed