Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.57 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27702337 | 0.99 | PREP (0.58) | PREPCYP2C19SMN1; SMN2FKBP1ACTRB1 | |
| SCHEMBL809457 | 0.96 | PREP (0.64) | PREPCYP2C19SMN1; SMN2CTRB1NPSR1 | |
| SCHEMBL475629 | 0.96 | PREP (0.64) | PREPCYP2C19SMN1; SMN2CTRB1NPSR1 | |
| SCHEMBL1437568 | 0.96 | PREP (0.64) | PREPCYP2C19SMN1; SMN2CTRB1NPSR1 | |
| SCHEMBL1056315 | 0.91 | SMN1; SMN2 (0.63) | PREPCYP2C19SMN1; SMN2CTRB1NPSR1 | |
| SCHEMBL1056316 | 0.91 | SMN1; SMN2 (0.63) | PREPCYP2C19SMN1; SMN2CTRB1NPSR1 | |
| SCHEMBL630208 | 0.89 | PREP (0.62) | PREPSMN1; SMN2FKBP1ACTRB1NPSR1 | |
| SCHEMBL630241 | 0.89 | PREP (0.62) | PREPSMN1; SMN2FKBP1ACTRB1NPSR1 | |
| SCHEMBL82714 | 0.89 | PREP (0.62) | PREPSMN1; SMN2FKBP1ACTRB1NPSR1 | |
| SCHEMBL7648948 | 0.88 | PREP (0.61) | PREPSMN1; SMN2FKBP1ACTRB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299821-A | HYPOTHERMIC AGENTS, TREATMENT OF NARCOLEPSY | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-11-10 | — | — | US | disclosed |