Sugi Predict

Sugi Predict / Compounds / SCHEMBL630241

SCHEMBL630241

SCHEMBL630241

O=C(O)C1CCCCN1C(=O)OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PREP P48147 3/20 0.62
▸ FKBP1A P62942 2/20 0.59
▸ CTRB1 P17538 1/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.57
▸ CTSB P07858 1/20 0.57
▸ CTSS P25774 1/20 0.57
▸ CTSK P43235 1/20 0.57
▸ NPC1 O15118 1/20 0.57
▸ RAB9A P51151 1/20 0.57
▸ TSHR P16473 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ KLK7 P49862 1/20 0.56
▸ KLK5 Q9Y337 1/20 0.56
▸ KDM4E B2RXH2 1/20 0.56
▸ LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630208 1.00 PREP (0.62) PREPFKBP1ACTRB1SMN1; SMN2ALDH1A1
SCHEMBL82714 1.00 PREP (0.62) PREPFKBP1ACTRB1SMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL29077433 0.99 PREP (0.61) PREPFKBP1ACTRB1SMN1; SMN2ALDH1A1
SCHEMBL7648948 0.99 PREP (0.61) PREPFKBP1ACTRB1SMN1; SMN2ALDH1A1
SCHEMBL7650461 0.99 PREP (0.61) PREPFKBP1ACTRB1SMN1; SMN2ALDH1A1
SCHEMBL7648946 0.99 PREP (0.61) PREPFKBP1ACTRB1SMN1; SMN2ALDH1A1
SCHEMBL29553 0.96 PREP (0.67) PREPCTRB1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL205223 0.96 PREP (0.67) PREPCTRB1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL29658848 0.96 PREP (0.67) PREPCTRB1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL475715 0.96 PREP (0.67) PREPCTRB1SMN1; SMN2ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745622-B Preparation method of aluminum nitride ceramic for printer heating strip 福建华清电子材料科技有限公司 2023-08-22 — — CN claimed
CN-115745622-A Preparation method of aluminum nitride ceramic for printer heating strip 福建华清电子材料科技有限公司 2023-03-07 — — CN claimed
US-20170101440-A1 METHODS OF TREATING OPHTHALMIC DISEASES USING NPR-B AGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-13 — — US claimed
US-20020037559-A1 PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES LONZA A.G. (CH) 2002-03-28 — — US claimed
JP-9067344-A — — None — — JP disclosed
JP-10120652-A — — None — — JP disclosed
US-20260109711-A1 MACROCYCLIC SULFONAMIDE MODULATORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-04-23 — — US disclosed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 — — US disclosed
US-12528801-B2 Substituted azacyles as TRPM8 modulators GIVAUDAN SA (CH) 2026-01-20 — — US disclosed
US-20260001885-A1 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS MERCK SHARP & DOHME (NL) 2026-01-01 — — US disclosed
US-11974999-B2 Bruton's tyrosine kinase inhibitors Liao, Xibin (US) 2024-05-07 — — US disclosed
US-20240132487-A1 SUBSTITUTED AZACYLES AS TRMP8 MODULATORS GIVAUDAN SA (CH) 2024-04-25 — — US disclosed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 — — EP disclosed
EP-0505868-A2 N-Acyl-alpha-aminoacids derivatives F. HOFFMANN-LA ROCHE AG (CH) 1992-09-30 — — EP disclosed
WO-1992006973-A1 INDOLE DERIVATIVES PFIZER INC. (US) 1992-04-30 — — WO disclosed
WO-1991018891-A1 AROMATIC PYRROLIDINE AND THIAZOLIDINE AMIDES PFIZER INC. (US) 1991-12-12 — — WO disclosed
US-4305949-A ANTIINFLAMMATORY AGENTS AND IMMUNOREGULATORY AGENTS PFIZER INC. (US) 1981-12-15 — — US disclosed
EP-0005070-B1 N-(2-THIAZOLYL)AMIDES AND THEIR USE AS ANTI-INFLAMMATORY AND IMMUNOREGULATORY AGENTS PFIZER INC. (US) 1981-12-09 — — EP disclosed
US-4217355-A N-(I-THIAZOLYL)-A-(SUBSTITUTED AMINO)AMIDES, ANTIINFLAMMATORY, IMMUNOREGULATIVE PFIZER INC. (US) 1980-08-12 — — US disclosed
JP-H00967344-A — — 0001-01-01 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 PREP 4757/4885FKBP1A 3276/4885CTRB1 3140/4885
US-20260109711-A1 MACROCYCLIC SULFONAMIDE MODULATORS HCRTR2, HCRTR1, CNR1 PREP 3970/4885FKBP1A 1060/4885CTRB1 782/4885
US-20240132487-A1 SUBSTITUTED AZACYLES AS TRMP8 MODULATORS TRPM8, TRPM7, TRPM5 PREP 4169/4885FKBP1A 1215/4885CTRB1 4211/4885
US-11974999-B2 Bruton's tyrosine kinase inhibitors BTK, ABL1, SYK PREP 3233/4885FKBP1A 569/4885CTRB1 3762/4885
US-12528801-B2 Substituted azacyles as TRPM8 modulators TRPM8, TRPM7, TRPM4 PREP 4807/4885FKBP1A 3388/4885CTRB1 3207/4885
US-20260001885-A1 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS BTK, ABL1, FLT3 PREP 1696/4885FKBP1A 2185/4885CTRB1 4247/4885
US-20170101440-A1 METHODS OF TREATING OPHTHALMIC DISEASES USING NPR-B AGONISTS NPR1, EDNRB, NPR3 PREP 826/4885FKBP1A 2144/4885CTRB1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.