Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858742 | 0.82 | ERN1 (0.54) | SMN1; SMN2ALDH1A1HTTALOX12MAPT | |
| SCHEMBL29365000 | 0.82 | ERN1 (0.54) | SMN1; SMN2ALDH1A1HTTALOX12MAPT | |
| SCHEMBL2775430 | 0.82 | HTT (0.58) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL2775429 | 0.82 | HTT (0.58) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL11521296 | 0.82 | HTT (0.58) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL30646074 | 0.78 | ERN1 (0.67) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL311105 | 0.78 | ERN1 (0.67) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12336953 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL14922836 | 0.77 | MAPT (0.43) | SMN1; SMN2ALDH1A1HTTALOX12MAPT | |
| SCHEMBL8942958 | 0.77 | MAPT (0.43) | SMN1; SMN2ALDH1A1HTTALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269702-A | Ore treatment process | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-26 | — | — | US | disclosed |