Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472150 | 0.98 | KDM4E (0.42) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL17616840 | 0.93 | MAPK1 (0.39) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL472104 | 0.88 | MIF (0.40) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL17616827 | 0.87 | CYP3A4 (0.49) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL12510737 | 0.85 | MAPK1 (0.33) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL17616828 | 0.83 | MAPK1 (0.39) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL12431720 | 0.82 | LMNA (0.42) | KDM4ETDP1ALDH1A1TP53CYP3A4 | |
| SCHEMBL17601883 | 0.80 | MAPK1 (0.42) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL17616839 | 0.80 | MAPK1 (0.42) | KDM4ETDP1MAPK1ALDH1A1PKM | |
| SCHEMBL12431716 | 0.79 | MIF (0.41) | KDM4ETDP1MAPK1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287100-A | VALUABLE AS FRAGRANCE MATERIAL | FRITZSCHE DODGE & OLCOTT INC. (US) | 1981-09-01 | — | — | US | disclosed |